4098 Relationship between salivary cotinine levels, oral health and lifestyle
K.D.P. BARNFATHER1, G. COPE2, and I.L.C. CHAPPLE2, 1The University of Birmingham, United Kingdom, 2University of Birmingham, United Kingdom

Smoking remains a major risk factor for oral diseases such as periodontal disease and the dental team have the potential to influence smoking behaviour patterns in substantial numbers of patients through practice-based smoking cessation counselling programs (Monaghan N. BDJ 2002: 193, 611-13). We have developed a 10-minute near patient test (NPT) for salivary cotinine (Nayar et al. Ann Clin Biochem 2000: 37, 666-73) and demonstrated improved quit rates through using the NPT during such practice-based programs. We have also shown that salivary cotinine values correlated positively with traditional measures of periodontal disease (Barnfather et al J Dent Res 2002: 81, 203). Objective: To examine the relationship between salivary cotinine values (SCV's) and measures of life-style and oral health. Methods: 100 smokers were recruited by random selection from those attending a general dental practice for this double-blind study. Subjects were asked to complete a questionnaire detailing smoking habit, alcohol consumption and related demographics. SCV's were determined by NPT assay as previously reported and relationships between SCV's, measures of oral health and life-style examined using Spearman's rank correlations. Results: There were significant correlations between SCV's and reported alcohol use (r=0.25, p<0.01), incidence of caries (r=0.25, p<0.01), CPITN scores (r=0.4, p<0.001), probing pocket depths (r=0.26 p<0.01), mobility, (r=0.34, p<0.001) and the presence of adverse oral mucosal change (r=0.26, p<0.01). Conclusion: Patients with high salivary cotinine values demonstrated a greater incidence of oral disease and also had less healthy lifestyles than those with low salivary cotinine values. Smoking habit, as assessed by a near patient test for salivary cotinine, reflects lower standards or oral care and lifestyle, both of which may contribute to reduced periodontal health.

This work was supported by a grant from the Oral and Dental Research Trust.

Seq #422 - Saliva as a Diagnostic Fluid
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