| 0487 Saliva and Plaque Characteristics of Low/high Caries Groups Following Prophylaxis | ||
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R.S. PERCIVAL1, D.A. DEVINE1, S.J. BROOKES1, M. JACKSON1, M. KELLETT1, B. WIEGAND2, J.C. ZGURIS2, L. JUNKER3, D.S. HARPER3, and P.D. MARSH4, 1Leeds Dental Institute, United Kingdom, 2Johnson & Johnson Consumer Companies Inc, Skillman, NJ, USA, 3Johnson & Johnson Consumer Companies Inc, Morris Plains, NJ, USA, 4Centre for Emergency Preparedness & Response, Salisbury, United Kingdom Introduction: Individuals display distinct susceptibilities to dental caries. Objective: the aim was to examine the hypotheses that (a) the composition of saliva and plaque from high and low caries prone subjects are different, and (b) following an intervention, these differences will be re-established. Methods: 52 subjects (age range: 18-39y) were subdivided into low (n=23; mean DMF = 1.3) and high (n=29; mean DMF = 10.7) caries experience groups. Salivary and plaque bacterial counts were taken, along with determinations of plaque pH, salivary flow rates and buffering capacity, and salivary IgA (sIgA), calcium and phosphate levels, at baseline and monthly up to five months after professional oral hygiene (supragingival prophylaxis). Results: There were no statistically significant differences in saliva biochemistry or flow rate between low and high caries groups, or within each group between baseline and five months after professional hygiene. There was a significant reduction in sIgA five months after the oral prophylaxis (p<0.04). Viable counts of mutans streptococci (saliva) and lactobacilli (plaque) were not significantly different at baseline (p>0.05; ANOVA) in the high versus the low caries group. However, following professional oral hygiene, viable counts of mutans streptococci in saliva were reduced and remained significantly lower than counts in the high caries group for 2 (p<0.05), 3 and 4 (both p<0.01) months after treatment. Viable counts of lactobacilli in plaque were significantly lower in the low caries group 5 months after professional oral hygiene (p<0.01). Conclusion: this study demonstrated that a supragingival prophylaxis was able to reduce viable counts of cariogenic bacteria in a low caries experience group for several months, but this effect was not observed in a group with high caries experience, indicating the need for multiple interventions for this group. This work was supported by a grant from Johnson & Johnson Consumer Companies Inc., USA | ||
| Seq #51 - Microbiology - Biofilms, Caries and Periodontal Disease. 11:30 AM-1:00 PM, Thursday, September 11, 2008 Queen Elizabeth II Conference Centre Poster Hall 2 | ||
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