| 0776 Antimicrobial Efficacy of Ozone in Root Canal Treatment | ||
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J. ALAWADI1, P.-J. LAMEY2, J.L. CUNNINGHAM3, H. DOMINGO4, E. LYNCH3, and M.C. GROOTVELD5, 1Queen's University of Belfast, United Kingdom, 2Queen's University Belfast, Northern Ireland, Uk, 3Queens University Belfast, Northern Ireland, Uk, 4Queens University Belfast, 5Bolton University, United Kingdom As ozone is the most powerful antimicrobial agent we could use in dentistry it seemed appropriate to assess its efficacy to help treat infected root canals. Huth et al (J Dent Res. 2007 86; 451-456) have reported a potential benefit of using Ozone in root canal treatment (RCT). Objectives: To assess the antimicrobial efficacy of sodium hypochlorite (0.5%) with and without the use of ozone in RCT irrigation in a double blind randomised controlled clinical trial. Material and Methods: After ethics committee approval, according to stringent inclusion/exclusion criteria, 100 patients were recruited in the study. Bacterial samples were taken at the baseline (D1) and after chemo mechanical preparation and irrigation (D2) using either sodium hypochlorite (NaOCl) with air (0.5%) (n = 38) or ozonated NaOCl (n = 42) with the air or ozone double blindly delivered from the HealOzone device (KaVo). Cultivable bacteria recovered from root canals were counted. Results: At baseline (D1), 80 samples were positive for bacteria, and the median numbers of bacteria was 17.000 (108-150.000) for the NaOCl group and 100.000 (13.750-500,000) for the ozonated NaOCl group. Sixteen (42%) canals from the NaOCl group and 27 (64%) canals from the ozonated NaOCl group yielded negative cultures. Chemomechanical preparation using either solution substantially reduced the number of cultivable bacteria in the canals. Mann- Whitney U tests indicated that there was a statistically significant difference observed between the NaOCl and ozonated NaOCl group in the percentages of bacterial reduction with significantly fewer microorganisms in the canal systems in the ozone group as measured by the median bacterial reduction. Conclusion: Both the irrigant groups had the ability to reduce the number of microorganisms in infected root canals in vivo and ozonated NaOCl had a more significant antibacterial activity in RCT as compared to NaOCl and air. | ||
| Seq #83 - Microbiology - Disinfection, Antibacterial actions 11:30 AM-1:00 PM, Friday, September 12, 2008 Queen Elizabeth II Conference Centre Poster Hall 2 | ||
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