0774 Chlorhexidine Mouthrinse versus Irrigation in the Prevention of Post-Extraction Bacteraemia
I. TOMÁS CARMONA1, M. BARBOSA2, B. AMARAL3, C. CERQUEIRA3, J. LIMERES1, P. DIZ1, and M. ALVAREZ4, 1Santiago de Compostela University, Spain, 2High Institute of Health Sciences, Oporto, Portugal, 3Santo Antonio General Hospital, Oporto, Portugal, 4Xeral-Cíes Hospital, Vigo, Spain

Objectives: To investigate the prevalence, duration and aetiology of bacteraemia following dental extractions (BDE) after a single prophylactic application of chlorhexidine (CHX).

Methods: The study group was formed of 150 patients who underwent dental extractions under local anaesthesia. Patients were randomly distributed into 3 groups:

-Control group: patients administered no CHX prophylaxis before dental extractions.

-CHX mouthrinse group: patients administered a 0.2% CHX mouthrinse (Oraldine Perio, Pzifer, Barcelona, Spain) for 1 minute before dental extractions.

-CHX mouthrinse/irrigation group: patients administered a 0.2% CHX mouthrinse for 1 minute and a 1% CHX subgingival irrigation before dental extractions.

Blood samples were collected at baseline, 30 seconds after the subgingival irrigation, 30 seconds and 15 minutes after the dental extractions. Samples were inoculated in BACTEC plus aerobic and anaerobic blood culture bottles, and were processed in the Bactec 9240. The subculture and further identification of the isolated bacteria were performed by conventional microbiological techniques.

Results: The prevalence of post-irrigation bacteraemia was 12%. The prevalences of BDE in the control, CHX mouthrinse group and CHX mouthrinse/irrigation group were at 30 seconds 51%, 50% and 56% respectively; at 15 minutes 23%, 4% and 10% respectively. Statistically significant differences were detected at 15 minutes between control and CHX mouthrinse groups (p= 0.008, Fisher exact test). The most frequently identified bacteria were Streptococcus viridans in the 3 groups (range 70-78%).

Conclusion: A 0.2% CHX mouthrinse reduces the duration of BDE performed under local anaesthesia, although the subgingival irrigation doesn't increase its efficacy. This confirms the convenience of administering a CHX mouthrinse before performing dental manipulations.

Seq #83 - Microbiology - Disinfection, Antibacterial actions
11:30 AM-1:00 PM, Friday, September 12, 2008 Queen Elizabeth II Conference Centre Poster Hall 2

Back to the PEF IADR 2008 Program
Back to the Pan European Federation of the International Association for Dental Research (September 10-12, 2008)

Top Level Search