Objectives: The aim of this prospective study was to evaluate and compare the clinical behavior of all-ceramic crowns fabricated partially by two different CAD/CAM systems. Methods: 94 all-ceramic anterior and posterior crowns were placed in 42 patients in a dental practice in Holland. Two different CAD/CAM systems made the copings of the crowns (46 Procera AllCeram and 48 CICERO copings). A general dental practitioner treated all patients and a dentist not involved with the treatments evaluated the crowns after a period of two years. The California Dental Association quality evaluation system was used for the clinical evaluation. X-rays, stone models and intra-oral photographs were also registered. The patients were requested to fill in a form with his/her personal opinion about the crown. Results: The marginal integrity was assessed excellent or acceptable for 92% of the crowns. The color was assessed excellent for 91% of the crowns according to the evaluator; the patients scored higher level of satisfaction. Endodontic treatment was not performed in any tooth after the cementation. Gingival condition did not change after the cementation of the crowns. Conclusions: This clinical evaluation demonstrates about the same clinical behavior and indicates a good prognosis of both CAD/CAM systems. The crowns based on Procera AllCeram and CICERO CAD/CAM aluminum oxide copings are applicable to all areas of the mouth during the first two years of use. This is particularly true in view of the very high patient satisfaction.

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