| 0222 Clinpro Cario L-Pop to measure the effect of an antimicrobial mouthrinse | ||
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M.J. BUIJS, J.M. TEN CATE, C. VAN LOVEREN, and V.A.M. GERARDU, ACTA, Amsterdam, Netherlands The Clinpro Cario L-Pop® (CCLP), a chair-side technique to evaluate caries risk, measures the lactic acid production in swab samples of the tongue flora. The results are read in a color range indicating a low, middle or high rate of lactic acid production. Objective: To measure the usefulness of CCLP to monitor the effect of an antimicrobial mouthrinse. Methods: Thirty volunteers used F-free toothpaste during 4 two-week periods. In between two of these periods a commercially available antimicrobial mouthrinse was administered for one week, twice a day immediately after brushing with fluoridated toothpaste. Six hours after the last brushing, CCLP-tests were performed. Four minutes after subsequent 2-minutes 10% sucrose rinse the tongue was sampled with a cotton swab for acid analysis with Capillary Ion Analysis (CIA). Results: From the CCLP-tests after the F-free periods 74% scored in the highest range, 10% in the lowest. 36% of the subjects scored in the same range at all 4 times whereas 72% had at least 3 scores in the same range. After one week usage of the mouthrinse, 40% of the tests scored in the lowest and 27% in the middle range. The CIA measurements revealed lactic acid concentrations of 7.8±2.5, 6.8±2.4, 7.7±3.5 and 8.6±4.1mM at the four F-free visits (intra-individual coefficient of variance 31±16%) and 2.2 ± 2.4 mM after the antimicrobial mouthrinse. Averaged over the F-free periods the individual CCLP readings were significantly correlated to the CIA measurements (r2 = 0.37, p<0.001), after the mouthrinse the correlation was better (r2 = 0.73, p<0.001). Conclusion: The acidogenic response of the tongue either assessed with CIA or CCLP varies over time. Both methods showed to be able to detect a shift to a lower acidogenic response when an antimicrobial mouthrinse was used. This study was supported by 3M ESPE Company. | ||
| Seq #22 - Cariology Research, Diagnosis, Microbiology and Fluoride 11:30 AM-12:45 PM, Friday, 27 August 2004 Crowne Plaza Hotel AVSA I | ||
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