Seq #156 Friday, March 23, 2007
10:45 AM-12:15 PM Ernest N. Morial Convention Center 283, Symposium - Group/Division Sponsored
Bridging the Biological and Material Science Disciplines to Build the Tooth

Sponsored by: Craniofacial Biology, Dental Materials, Mineralized Tissue
Description: The endeavor of tooth regeneration has attracted the attention of many investigators in the field of dental and biomedical research. This multidisciplinary symposium will address different aspects of this rapidly growing field. The objective of this symposium is to promote communication between investigators from different disciplines including developmental and stem cell biology, biomechanics, biomimetics, and biomaterial sciences, to address the opportunities and challenges involved. All the selected speakers have been directly or indirectly involved with the NIDCR initiative; “Building the Tooth: Bridging Biology in Material Sciences”. Dr. Eleni Kousvelari from the NIDCR will give the introductory remarks. The first presenter will cover the signaling pathway of critical molecules as the firm foundation to understand tooth organogenesis. The second presentation will address the strategy of using minipig model for the study of mesenchymal stem cell-mediated dental tissue regeneration. The third presenter will focus on the design and synthesis of artificial
 tooth-like and bone-like composite materials and on the development of biomimetic strategies for dental tissue regeneration, using nacre and natural mineralized tissues as a guide. The last speaker, Dr. Zaslansky will describe the application of a novel technique; laser interferometer to provide details of the microstructure of dentin spanning hundreds of microns below the enamel, and the relation to whole tooth deformation in response to forces of mastication. The technique has a great potential to be applied for characterization of an engineered tooth. Because of its multidisciplinary nature we anticipate a wide variety of audience to participate in this symposium. Sufficient time will be allowed for general discussion at the end of all four presentations.
Chairpersons: J. MORADIAN-OLDAK and T. DIEKWISCH
 
1350  10:45 AM Introductory Remarks
E. KOUSVELARI, National Institute of Dental and Craniofacial Research, Bethesda, MD, USA
  10:50 AM Early Odontogenetic Signaling Pathways: Relevance to Tooth Regeneration
R. MAAS, Harvard University, Boston, MA, USA
  11:10 AM Mesenchymal Stem Cells And Dental Tissue Regeneration
S. SHI, USC CCMB, Los Angeles, CA, USA
  11:30 AM Novel Strategies For Dental Tissue Regeneration Inspired by Nacre
A. TOMSIA, Lawrence Berkeley National Laboratory, CA, USA
  11:50 AM Structure Deformation Relations of Whole Human Tooth
P. ZASLANSKY, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany

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