| 1218 Prevalence and Risk Factors Associated with Fissured Tongue | ||
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W.M. CARPENTER, University of the Pacific, San Francisco, CA, USA, and J.D. SHULMAN, Baylor College of Dentistry, Dallas, TX, USA Fissured Tongue (FT) is a relatively common, benign condition manifested by numerous small furrows (grooves, fissures) on the dorsal surface of the tongue that often radiate from a central groove along the midline. Considerable variation exists and these fissures usually range from 2-6 mm in depth. The etiology is unclear but heredity and/or aging may be factors. Objectives: To report FT prevalence in adults participating in the Third National Health and Nutrition Examination Survey 1988-1994 (NHANES III), a large US study based on multistage probability sampling. Methods: Oral examinations were performed by dentists using World Health Organization criteria for diagnosing FT; a health interview was performed, and blood was drawn at examination. Bivariate and multivariate logistic regressions were performed using SAS-callable SUDAAN 9.0.1. All analyses accounted for the design effect and yielded unbiased standard error estimates. Results are presented in terms of unadjusted (OR) and adjusted odds ratios (AOR). Results: FT was found in 194 of 16,833 adults (point prevalence 0.91%). Higher FT prevalence was found in males (1.11%) (OR=1.55; 95% CI: 1.07 - 2.23) than females (0.72%); individuals with low (<12 ng/mL) ferritin (OR=3.15; 1.15 - 8.60); geographic tongue (GT) (OR = 10.38; 4.55 - 23.67); diabetes history (OR=2.45; 1.46 - 4.03); AGE: <60 (OR=11.79; 4.10 - 33.92); 40-59 (OR=5.32; 1.94 - 14.54) compared to 17-39 years; Whites (OR=2.11; 1.28 - 3.51) compared with Blacks. A multivariate logistic model adjusted for AGE and AGE2 showed that males with GT had the highest AOR (21.45; 9.34 - 49.25), followed by females with GT (AOR=6.25; 2.30 - 16.93); and males with no GT (AOR = 1.41; 0.92 - 2.15) compared to females without GT. Conclusions: These findings are consistent with the current associations reported of FT with aging, male gender and GT. Further genetic studies may determine the exact etiology. | ||
| Seq #129 - Clinical Diseases and Pathogenesis 3:30 PM-4:45 PM, Thursday, March 22, 2007 Ernest N. Morial Convention Center Exhibit Hall I2-J | ||
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