| Seq #116 | Friday, 10 March 2006 | |||||||||||||||||||||||
| 10:45 AM-12:15 PM Dolphin Hotel No. Hemis A-4, Symposium - Group/Division Sponsored | ||||||||||||||||||||||||
| [AADR] Genetic Diseases Affecting Primarily the Dentition | ||||||||||||||||||||||||
Sponsored by: Mineralized Tissue | ||||||||||||||||||||||||
| Description: This symposium discusses recent advances in our understanding of “Genetic Diseases Affecting Primarily the Dentition”. The type of inherited dental malformations observed in a patient or kindred relate to when, during odontogenesis, the defective gene is critically expressed. Genes affecting early tooth development, PAX9, MSX1, AXIN2, and PITX2, are associated with familial tooth agenesis or oligodontia. Genes affecting dentin formation, COL1?1, COL1?2, and DSPP, are associated with the dentinogenesis and osteogenesis imperfectas and dentin dysplasia. Genes affecting enamel formation, AMELX, ENAM, MMP20, and KLK4, are associated with amelogenesis imperfecta. Genes affecting root formation, ALPL and DLX3, are associated with cementum agenesis (hypophosphatasia) and taurodonism. The presentations are aimed at dental clinicians and basic scientists alike. The symposium will provide a better understanding of normal tooth development as well as the pathological basis of inherited diseases that interfere with the development and/or biomineralization of teeth. This program is financially supported by Procter & Gamble and the University of Michigan School of Dentistry | ||||||||||||||||||||||||
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Back to the ADEA/AADR/CADR Meeting & Exhibition (March 8-11, 2006)