Seq #91 Thursday, 29 June 2006
1:30 PM-3:30 PM Brisbane Convention & Exhibition Centre P2, Symposium - Group/Division Sponsored
Molecular Signaling in Oral Cancer: Implications in Cancer Therapy

Sponsored by: Oral Medicine & Pathology
Description: The symposium will consist of lectures by four scientists focused on signaling pathways in oral cancer. In spite of advancements in surgery, radiation and chemotherapy, only about half of individuals diagnosed with oral cancer will survive for five years. However, recently there has been major progress in our understanding of the molecular signaling pathways involved in tumorigenesis and tumor progression. The main objective of this symposium is to bring together experts from the related areas of cell signaling and present new findings related to oral cancer. Speakers will highlight progress in areas that include signaling pathways in growth factor and adhesion receptors, apoptosis and survival, proliferative signaling pathways, and angiogenesis. The potential for targeting these areas for therapeutic intervention will also be addressed. We anticipate that this timely international symposium will bring together a diverse group of clinicians and basic scientists as well as students and postdoctoral fellows. It is hoped that the lectures will stimulate discussion among new and established investigators,encourage collaborative and multidisciplinary studies, and enhance translational research
Chairperson: C.-Y. WANG
 
1055  1:30 PM Regulation of Invasion and Survival in Oral SCC Cells by Cell Adhesion Receptors
R.H. KRAMER, University of California, San Francisco, USA
  2:00 PM Induction of Apoptosis in Oral SCC Cells by inhibiting NF-kB: Implications in Cancer Therapy
C.-Y. WANG, University of Michigan, Ann Arbor, USA
  2:30 PM Overcoming Endothelial Cell Resistance with Signaling Inhibitors: Opportunity for Improved Tumor Therapy
P.J. POLVERINI, University of Michigan, Ann Arbor, USA
  3:00 PM Regulation of Oral Cancer Growth and Progression by Akt/mTOR Signaling
J.S. GUTKIND, National Institute of Dental and Craniofacial Research, Bethesda, MD, USA

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