| 2481 Bone Kinetics Around Various Implant Surfaces at Early Implantation Time | ||
|
P.G. COELHO, New York University, USA, J.N. FREIRE, Private Practice, Florianopolis, Brazil, A.L. COELHO, UNICENP, Curitiba, Brazil, and J. LEMONS, University of Alabama -, Birmingham, USA Objective: to evaluate bone kinetics adjacent to the surface of Alumina-Blasted/Acid-Etched surface implants, 30-50nm nanothick Ion Beam Assisted Deposited bioceramic coated implants (IBAD1), 300-500nm nanothick Ion Beam Assisted Deposited bioceramic coated implants (IBAD2), and Plasma Sprayed Hidroxyapatite (PSHA) coated implants. Materials and Methods: AB/AE, IBAD1, IBAD2, and PSHA coated implants were sequentially placed at the proximal tibia of six beagle dogs. The implants remained for 3 and 5 weeks in-vivo. Oxytetracicline and Calcein Green were administered at 10 and 2 days prior to euthanization respectively for MAR assessment. After euthanization, the limbs were retrieved and nondecalcified thin sections prepared for microscopy. MAR assessment was performed at bone regions from 0 to 0.5 mm away from the implant surface at both sides of the implant by means of computer software (Bioquant NOVA, Nashville, TN). Physiologic MAR was assessed at regions away from the implant surface. One-way ANOVA at a 95% level of significance was utilized for MAR comparison between implant surfaces. Results: MAR results for 3-weeks implantation time were AB/AE=3.01 ±0.07a μm/day IBAD1=2.85±0.07b μm/day, IBAD2=3.00±0.08a,b μm/day, PSHA=2.85±0.07b μm/day, and physiologic=2.5 ±0.04c μm/day. MAR results for 5-weeks implantation time were AB/AE=2.412±0.06c μm/day IBAD1=2.80±0.07a μm/day, IBAD2=2.65±0.05b μm/day, PSHA=2.67±0.06a,b μm/day, and physiologic=2.36 ±0.04c μm/day. Conclusion: Bone kinetics around implants at early implantation times was surface treatment dependent. AB/AE surface implants presented significantly higher MAR values at 3-weeks in-vivo compared to bioceramic coated implants. However, AB/AE surface implants' MAR dropped to physiologic values at 5-weeks implantation time, whereas bioceramic-coated implants maintained high MAR values. Sustained high MAR values around bioceramic coated implants may result in faster bone modeling/remodeling and high biomechanical fixation degrees at early implantation time in-vivo. | ||
| Seq #200 - Cell Culture & Bone Formation 8:00 AM-10:00 AM, Saturday, 1 July 2006 Brisbane Convention & Exhibition Centre M1 | ||
|
Back to the Implantology Research Program
| ||