Seq #6 Wednesday, 9 March 2005
2:00 PM-4:00 PM Baltimore Convention Center 340-341, Symposium - Joint with ADEA
Interplay of Bacteria, Genetics and Risks in Pathogenesis, Diagnosis, and Treatment of Periodontitis

Sponsored by: Microbiology / Immunology and Infection Control, Periodontal Research
Description: The Symposium will focus on the interactions among bacterial challenge, individual genetic traits and other risk factors such as smoking as major determinants in the pathogenesis, diagnosis and treatment of periodontitis. The Symposium is directed toward basic science investigators in the fields of periodontal pathogenesis, microbiology, immunology and genetics as well as those interested in host susceptibility and in translation of basic information to periodontal diagnosis and generation of individualized, needs-based treatment plans that enable application of the well ness model of periodontal care. Speakers hope to clarify the interactions among bacterial infection, host genetic and other environmental risk factors and demonstrate application of this information to the diagnosis and treatment planning for periodontal diseases. Chronic periodontitis is the result of complex host responses to infection by communities of pathogenic bacteria residing in protective subgingival biofilms. The composition and behavior of these communities relate to local tissue status, host genetic traits and environmental factors. The effects of various periodontal therapies on these communities will be discussed. The bacteria alone are insufficient to cause disease; a susceptible host is also essential. Fifteen candidate genes have been studied will be considered with emphasis on interleukin-l and Fc-gamma receptor genes. Practical integration of knowledge of genetic and other risk factor information will be discussed as it relates to clinical management of chronic periodontitis. Information technology can now be used to measure and express risk and disease extent and severity as numeric values. These values can be used to integrate risk into the diagnosis and generation of needs-based treatment plans that enable application of the wellness model of periodontal care
Chairpersons: P.M. BARTOLD and P.B. ROBERTSON
 
  2:00 PM Chair's Opening Remarks
0006  2:10 PM Etiology and Control of Periodontal Infections
S. SOCRANSKY, The Forsyth Institute, Boston, MA, USA
  2:40 PM Nuture Your Nature; Role of Genetic Factors in Pathogenesis and Diagnosis
K. KORNMAN, Interleukin Genetics, Inc, Waltham, MA, USA
  3:10 PM Use of Numeric Values in Diagnosis and Treatment Planning for Periodontitis
R.C. PAGE, University of Washington, Seattle, USA
  3:40 PM Discussion

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