Seq #8 Wednesday, 9 March 2005
2:00 PM-4:00 PM Baltimore Convention Center 339, Symposium - Group/Division Sponsored
Molecular Basis of Immunoregulation--Impact on Oral Health

Sponsored by: Microbiology / Immunology and Infection Control
Description: Developmental and regulatory processes can control the activity of the immune system at multiple levels. Both host factors such as cytokines, and bacterial factors such as pathogen-associated molecular pattern molecules, can influence the development and function of lymphocytes and other immune cells. The outcome of these interactions can have a significant impact on oral health status, and contributes to either the restraint of pathogen activity or immune dependent tissue destruction. This symposium will bring together current concepts of the molecular basis of immune regulation and its relevance to oral diseases that have an immunological component, such as periodontal disease. Through a progressive series of talks spanning immune function and regulation through bacterial-immune cell interactions, the complex command and control mechanisms that regulate immune status will be dissected. Topics to be covered include: cytokine signaling, interleukin 17 and bone loss, LPS induced signal transduction, and pattern recognition of P. gingivalis. This symposium is targeted to investigators in the fields of oral immunology, microbiology and pathology
 
  2:00 PM Welcoming Remarks
0008  2:05 PM Cytokine Signaling - Basic and Applied
J. O'SHEA, NIH/NIAMS, Bethesda, MD, USA
  2:55 PM Interleukin-17 in Bone: Gene Expression and Role in Alveolar Bone Loss
S. GAFFEN, University of Buffalo SUNY, NY, USA
  3:15 PM A Role for Moesin in LPS Signal Transduction
T.E. VAN DYKE, Boston University, MA, USA
  3:35 PM Pattern recognition/capture of P. gingivalis by human myeloid DCs
C.W. CUTLER, State University of New York - SUNY - Stony Brook, USA

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