2281 New bioactive glasses in oral surgery. XPS and sputtering study
D. CICCIÙ, G. LO GIUDICE, G. OTERI, P. CATALANO, and M. CICCIÙ, University of Messina, Italy

Objectives: The purpose of this preliminary study was to evaluate the ability of a new bioactive glass-ceramic material to improve healing time of bone defects deriving from oral surgery. The osteoconductive and osteoinductive potential of this bioglass (containing biological glass, glycerol , bidistilled water and pure gelly) is based on ion exchanges between body fluids and biomaterial surface. Methods: To get confirmation of these properties an experimental study on sample of this new biomaterials (Crystal Biotech A - Thech-Medical) was carried on, using a surface analysis (XPS) associated whit a sputtering by ionum Ar+ till a depth of 2000 A°. The evaluation of the present elements on the analysed surface and the depth outlines was carried on before and after the immersion of the sample in a simulated body fluid (SBF), for 12 h, 24 h and one week. The value of the concentration of superficial ioniums checked and evaluated by graphic of the spectrum XPS has been compared with the intensity of Si²P. Results: The analysis of the spectrums XPS of surfaces samples before the immersion into SBF shows a considerable presence of Si; after sputtering Na, Ca, P are the most present elements. The XPS spectrums of the bioglass samples after the immersion into SBF evidenced on the surface the increase of concentration especially of Ca, P and Na ionums coming from deep coats and a decrease of concentration of Si. After sputtering, in deep coats, we noticed the Ca, P and Na decrease and the Si increases. Conclusion: Preliminary results of this in vitro study attest the property of these new bioglasses interact with biologic liquids through ionium changes.

Seq #248 - Reconstruction, Wound Healing
2:00 PM-4:00 PM, Friday, 11 March 2005 Baltimore Convention Center Exhibit Hall E-F

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