| 0252 Association between Dental Caries Activity and Coronary Heart Disease Severity | ||
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H.D. SGAN-COHEN1, M.N. SELA1, M. ANGIE1, and M. MOSSERI2, 1Hebrew University - Hadassah School of Dental Medicine, Jerusalem, Israel, 2Hebrew University - Hadassah School of Medicine, Jerusalem, Israel The link between dental diseases and a wide range of systemic medical conditions has recently acquired increased attention. Periodontal disease, in particular, has been implicated as a marker of cardiac disease. Dental caries, the most common oral infection, should be considered as a potential risk factor for all systemic diseases. Few studies have investigated this association. Objectives: To investigate the potential relationship between dental caries activity, dental plaque levels and presence of mutans streptococci (Ms) in saliva (independent variables) and coronary heart disease (CHD) severity (dependent variable). Methods: 219 cardiac patients in a hospital cardiac clinic were included. Dental caries activity was evaluated by the "D" or "untreated" component of the DMFT index , dental plaque was measured according to the Turesky index, and the number (CFU\ml) of salivary Ms were measured on MSB-agar. CHD severity was assessed according to extent of vessel blockage; function and size of left ventricle according to results of LV-Gram catheterization; Stress tests were categorized by physiological symptoms of CHD; previous hospitalization (due to CHD) was recorded. Results: Previously hospitalized patients due to CHD had 3.03 untreated carious teeth as compared with 1.84 among patients not previously hospitalized (Mann-Whitney, p=0.032). Levels of MS were lowest among patients who had no coronary blockage: 11.63 million CFU\ml, as compared to patients with single, double, or triple vessel blockage: 12.97, 30.64, 21.11 million CFU\ml respectively (ANOVA, p=0.031). Plaque index levels were lowest among patients with no coronary blockage (2.80) as compared with patients with single, double or triple vessel blockage: 3.56, 3.31, 3.54 respectively (ANOVA, p=0.049). Conclusions: These data consistently indicate a potential association between dental caries activity and CHD severity and emphasize the role of preventive dentistry in the promotion of general health.
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| Seq #56 - Epidemiology 10:45 AM-12:45 PM, Thursday, 10 March 2005 Baltimore Convention Center 331 | ||
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