| 3411 Optimism Protects Against Osteoporotic Hip Fractures | ||
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G. LANDA1, O. LEVY1, K. ATCHISON1, S.C. WHITE1, S. SERVICE2, and A. PAGANINI-HILL3, 1University of California - Los Angeles, USA, 2UCLA School of Medicine, Department of Biomathematics, Los Angeles, CA, USA, 3USC Keck School of Medicine, CA, USA Objective: Recent literature has demonstrated an association between a person's attitude and alterations in BMD and rate of vertebral fractures. The purpose of this study is to determine the association between an older individual's optimism and hip fracture. Methods: 13,979 residents of a California retirement community joined the Leisure World Cohort Study in 1981-85 by completing a baseline questionnaire asking demographic information, life-style practices, health-screening behaviors, health status, hormone use, and diet. Additionally, responses to 4 items about positive attitudes, measured on a 4-point scale, were summed to a composite optimism scale (4-16 points). Subjects were divided into three ‘optimism' groups (1: 4 –11, 2: 12-15, 3: 16 points). Hip fracture data was obtained from combined self-report and hospital discharge data over the following two decades. Cox proportional hazard regression was performed to determine the added contribution of the optimism scale to a core model (age, sex, weight, history of fracture, sex*weight) predicting risk of hip fracture. Results: Of the 8,385 women and 4,865 men who completed the optimism scale, 1,446 sustained a subsequent hip fracture. Optimism was significantly correlated with the hip fracture incidence (p<0.0001). After adjusting for the core variables, the hazard ratios for optimism were 0.939 for women and 0.900 for men. Subjects in group 3 had 1.08 and 0.45 fractures per 100 person-years of follow up for women and men respectively compared to 1.47 and 0.76 fractures for group 1. Conclusion: This study provides evidence that an optimistic attitude is a protective factor for hip fracture. Therefore, future work devising a dental screening tool for osteoporosis should consider the patient's attitude. Acknowledgement: Support was received from R01 AR 47529 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892. | ||
| Seq #355 - Stress, Health Promotion, and Clinical Trials 10:15 AM-11:30 AM, Saturday, 13 March 2004 Hawaii Convention Center Exhibit Hall 1-2 | ||
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