Exercise as a Protective Factor Against Osteoporotic Hip Fracture

*3410 Exercise as a Protective Factor Against Osteoporotic Hip Fracture*
A. SAADAT¹, F. YOUSEFZADEH¹, K.A. ATCHISON¹, S.C. WHITE¹, S.K. SERVICE¹, and A. PAGANINI- HILL², ¹University of California - Los Angeles, USA, ²USC Keck School of Medicine, Los Angeles, CA, USA Objectives: For the osteoporotic individual, exercise is encouraged as a valuable aspect of treatment to maintain or increase bone strength. The purpose of this study was to examine the relationship between active exercise and hip fracture among an elderly cohort. Methods: An epidemiologic cohort in a California retirement community was recruited in 1981-1985. Participants completed a series of questionnaires about birth date, sex, medical history including fractures after age 40, and life-style habits including the amount of time engaged in exercise daily. Over 20 years of follow-up by self-report and hospital discharge data provided information on subsequent hip fractures. Cox proportional regression was used to test the effect of daily active exercise on fracture risk. Results: Of the 13,700 cohort members with exercise data and follow-up information 1,496 sustained an incident hip fracture during the study. The mean time per day spent in active exercise reported was 2.1 hours (s.d. 2.55 hours, range 0 - 13 hours). 10,376 reported exercising daily. A core model found that sex (hazard ratio 5.189), age (hazard ratio 1.086), and history of fracture (hazard ratio 1.488) were all positive risk factors for incident hip fracture. The interaction of sex and weight yielded a hazard ratio of 0.983, indicating higher weight decreased likelihood of fracture. The additional contribution of daily active exercise yielded a hazard ratio of 0.943, making active exercise a protective factor against hip fracture. Conclusion: We confirmed that active exercise is a protective factor and may help prevent hip fracture in both older men and women. Dental offices may want to consider asking about active exercise as a component of screening for osteoporosis. Acknowledgement: Support was received from R01 AR 47529 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892.
Seq #355 - Stress, Health Promotion, and Clinical Trials 10:15 AM-11:30 AM, Saturday, 13 March 2004 Hawaii Convention Center Exhibit Hall 1-2
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