Objective: The aim of this prospective study was to evaluate the outcome of TPS-SteriOss® implant supported fixed partial dentures (FPD) after a mean observation period of 5-years. Methods: Two-hundred and sixty-two two-stage TPS-SteriOss® implants were placed in 82 partial edentulous patients and restored with 4 single-, 57 splinted- (2 units) and 48 splinted- (3 units) ceramic-metal crowns. Clinical evaluation started at the insertion of fixed partial dentures (FPD) and was repeated at 6 months intervals. The Kaplan-Meier estimator was used for evaluation of annual success rates. A failure was one of the following technical complications: screw loosening, screw fracture, or ceramic flaking. Results: Two-hundred eleven implants, placed in 61 patients (female:39, male:32), restored with 3 single-, 48 splinted- (2 units) and 37 splinted (3 units) ceramic-metal crowns, were clinically evaluated after a mean observation period of 60 months. 88 Supra-Fix® and 12 Bredent® screws were used for horizontal fixation of the FPD. The drop-out rate was 25.6%. The estimated overall success rate of the FPD was 91% after 5 years. The estimated survival rate for single crowns was 75%, for splinted crowns (2 units) 89.6% and 94.6% for splinted crowns (3 units). The following technical complications occurred: screw loosening (4), screw fracture (2) and ceramic flaking (4). Conclusion: It can be concluded that the long-term success of TPS-SteriOss® implant-supported restorations can be improved by splinting the ceramo-metal crowns. This study was supported by SteriOss® (Yorba Linda, CA, USA)

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