| 3499 Effect of surface modification on titanium surfaces by plasma treatments | ||
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S.-Y. LEE1, K.-L. OU2, Y.-N. LIN1, M.-S. CHEN1, C.-H. CHEN1, and C.-T. LIN1, 1Taipei Medical College, Graduate Institute of Oral Rehabilitation Sciences, Taiwan, 2Taipei Medical College, Graduate Institute of Oral Sciences, Taiwan Objectives: in order to improve the implant integration, it is desirable to control interfacial reactions such that nonspecific adsorption of proteins is minimized and tissue-healing phenomena can be controlled. In this study, our purpose was to develop a new method to functionalize titanium surfaces by plasma treatment. Methods: argon plasma was used to post-treat titanium plate to eliminate surface contaminants and to produce a consistent and reproducible titanium oxide surface layer. Then an intermediary allylamine deposition was covalently linked to the oxide layer by glow discharge, followed by the covalent binding of albumin to the free terminal NH2 groups using glutaraldehyde as a coupling agent. Plasma-treated titanium surface were analyzed by SEM, XRD, EDS and XPS. Results: based on the above investigation, it can be seen that the longer plasma-treated time is, the smoother the surface is. It is believed that bombardments of energetic radicals and ions during plasma treatments could sputter and clean the surface and make it smooth. Chemical compositions of plasma treatment and deposition were analyzed by XPS. The presence of the N 1s peak shows that the surface was nitrided by plasma treatment. It revealed that allylamine with terminal NH2 groups was successfully linked with plasma-treated Ti plate. The allylamine was ionized by plasma treatment process, and dangling bond was acted as medium to linking albumin. Conclusion: the plasma treatment process plays an important role in helping tissue-healing phenomena. It can be not only provided clean titanium surface, but also make dangling bond NH2 on plasma-treated Ti surface. It was better for linking glutaraldehyde and albumin absorption on Ti surface. It revealed that surface cleaning by ion bombardment and surface modification by chemical polymerization are believed to remove contamination on titanium surfaces and hence promote tissue healing. | ||
| Seq #360 - Biomechanics/Implant Surfaces 10:15 AM-11:30 AM, Saturday, 13 March 2004 Hawaii Convention Center Exhibit Hall 1-2 | ||
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