| Seq #144 | Friday, 14 March 2003 | |||||||||||||||||||||||||||||||
| 1:45 PM-3:45 PM Henry B. Gonzalez Convention Center Room 212, Symposium - Group/Division Sponsored | ||||||||||||||||||||||||||||||||
| Regulation of Epithelia-MesenchymaI Transformation in Palate Development and Tumor Metastasis | ||||||||||||||||||||||||||||||||
| * Poster files available online | ||||||||||||||||||||||||||||||||
Sponsored by: Craniofacial Biology, Oral Medicine & Pathology | ||||||||||||||||||||||||||||||||
| Description: 1) Overview: Many of the same signal transduction pathways are utilized in health and disease. A comparison of their use and mechanisms promises improved understanding of craniofacial development and various diseases processes. One important cellular/developmental mechanism is epithelial-mesenchymal transformation (EMT). This symposium will explore and contrast similar EMT-related signal transduction pathways during one normal developmental process, palate morphogenesis, and during the metastasis of epithelial tumors. 2) Level of investigator at which this symposium is aimed: The symposium’s aim is to provide an overview of this important area to all interested biomedical scientists involved in dental research. The symposium will provide basic information for those that work in cognate areas, and will specifically stimulate discussion between those working in areas of craniofacial development and tumorigenesis. 3) What is hoped to be achieved: The symposium will achieve a more in depth understanding of similarities in signal transduction mechanisms between studies of craniofacial developmental and tumorigenesis. It will stimulate discussion between those conducting research in these two areas. 4) Aspects of the subject that this symposium will cover: The symposium will provide an introduction to EMT and signal transduction, followed by more in depth discussions of similar signal transduction pathways during EMT in palate development and in tumorigenesis, including TGF ß3 signaling, PI3-kinase signaling, and integrin signaling. Tumorigenesis models will include discussions of oral and mammary tumors | ||||||||||||||||||||||||||||||||
| Chairperson: K.K. SVOBODA | ||||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||||
Back to the: Symposium Program
Back to the 32nd Annual Meeting and Exhibition of the AADR (March 12-15, 2003)