Antimicrobial and Mechanical Properties of Resin Cements Containing Silver-Zinc Glass or Zeolite

1288 Antimicrobial and Mechanical Properties of Resin Cements Containing Silver-Zinc Glass or Zeolite

X. QIAN, T.T. NGUYEN, and D. TOBIA, Kerr Corporation, Orange, CA, USA

Two antimicrobial agents (a silver-zinc glass SG and a silver-zinc zeolite SZ) were incorporated into an experimental clear resin cement (EXP) to impart antimicrobial property to the cement. Objectives: to measure the bacterial growth inhibition and flexural strength (FS) of EXP, EXP with 5% SG (EXP+SG), EXP with 0.4% SZ (EXP+SZ), and a commercial cement Calibra (CAL). Methods: Bacterial growth inhibition test was conducted according to a modified AATCC 100 method. Specimens (n=3) of square plates (38x38x0.5mm) were prepared and inoculated with Streptococcus mutans. Colony forming units (CFU) were determined at zero-contact time and after 24-hours incubation at 37° C, and percent of bacterial reduction was calculated. The flexural testing was conducted according to ISO 4049 standard. Results: ANOVA analysis revealed that both EXP+SG and EXP+SZ had significantly (p<0.05) lower CFU's after 24-hr contact time and higher percent of bacteria reduction than CAL and the control EXP. The FS's of EXP and EXP+SZ are not significantly different from each other, but significantly higher (p<0.05) than those of EXP+SG and CAL.

Cement

Antimicrobial Agent

CFU, 10²

Percent of Bacteria Reduction(%)

FS, MPa

Zero Contact Time

24-hr Contact Time

EXP

None

1667± 58^a*

9933± 3580^b

-499± 224^b

165± 10^a

EXP+SZ

0.4% SZ

1733± 58^a

2.2± 3.8^a

99.9± 0.2^a

160± 15^a

EXP+SG

5% SG

1833± 58^a

4.0± 6.9^a

99.8± 0.4^a

135± 12^b

CAL

unknown

1750± 71^a

7500± 1980^b

-327± 96^b

132± 12^b

*Means with the same letter within the same column are not statistically different at p<0.05.

Conclusions: Both EXP+SG and EXP+SZ exhibited strong antimicrobial effects and almost 100 percent bacterial reduction was achieved with both experimental cements. CAL and the control EXP showed no antimicrobial effect and the bacterial count increased by 300-500%. The mechanical properties of all experimental cements are either better or comparable to the commercial cement CAL.

Seq #163 - Other Ceramics and Cements
3:45 PM-5:00 PM, Friday, 14 March 2003 Henry B. Gonzalez Convention Center Exhibit Hall C

Back to the Dental Materials: III - Ceramics and Cements Program
Back to the 32nd Annual Meeting and Exhibition of the AADR (March 12-15, 2003)

Top Level Search