| 1128 Effects of Cigarette Smoking and Alcohol on HIV-related Oral Lesions | ||
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T. ALPAGOT, and D.W. CHAMBERS, University of the Pacific School of Dentistry and University of California School of Dentistry in San Francisco, USA Objectives: The study aim was to identify the effect of smoking and alcohol use on HIV-related oral lesions in a cross-sectional study. Methods:Oral examinations were performed to assess the prevalence of oral lesions in 152 HIV+ patients and 40 HIV- control subjects. Results: Oral candidiasis, pseudomembranous and/or erythematous, was the most common oral lesion among HIV+ patients (27.3%), followed by hairy leukoplakia (18.6%), exfoliative cheilitis (13.7%), and linear gingival erythema (LGE) (12.1%). After adjusting for CD4 cell count and viral load, current smokers were significantly more likely to have oral candidiasis (OR = 2.45 and 95% CI = 1.94-3.52), hairy leukoplakia (OR = 2.19 and 95% CI = 1.45-3.14), exfoliative cheilitis (OR = 1.92 95% CI = 1.42-2.61), and LGE (OR = 1.71 95% CI = 1.33-2.29) than were current nonsmokers in HIV+ group. Alcohol consumption was a significant risk factor for the presence of oral candidiasis (OR = 2.27 95% CI = 1.62-3.25). Conclusion: The results suggest a strong association between cigarette smoking/alcohol use and the presence of specific oral lesions. This study was supported by NIDCR grant DE12417 | ||
| Seq #142 - Diagnosis and Mechanisms of Oral Diseases 11:00 AM-12:15 PM, Friday, 14 March 2003 Henry B. Gonzalez Convention Center Exhibit Hall C | ||
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