Dentin hypersensitivity is frequently observed after periodontal scaling and root planing. Objective: to compare the effectiveness of a single topical application of a calcium phosphate solution (Quell ^TM Desensitizer, Pentron Clinical Technologies, Wallingford, CT) [test] to sodium fluoride gel (Nupro ^® Neutral, Dentsply, York, PA) [control] in patients having hypersensitivity following periodontal therapy. Methods: The clinical trial was of a prospective, convenient, double-blind design having 30 patients (M=15, F=15), with a total of 40 teeth treated with the test product and 40 treated with the positive control product. Clinical parameters measured at baseline and in the follow-up visits (1, 2, and 4 weeks after treatment)included: plaque index (Pl.I), gingival index (G.I), gingival recession, and response to mechanical and cold stimulation with airblast and ice. Patients reported the grade of pain response on a Visual Analogue Scale (VAS). Results: Pl.I and G.I. were not significantly different between both groups throughout the study. Acidic diet seemed to favor dentin hypersensitivity. Buccal surfaces evoked higher pain response compared to lingual. When hypersensitivity treatment outcomes were compared for test and control groups by the Mann-Whitney test or Students't-test, no statistically significant differences were found. Conclusion: Both positive control and test treatments reduced dentin hypersensitivity to mechanical and/or cold stimulation and were not statistically different. Supported in part by Pentron Clinical Technologies.

Back to the Pharmacology, Therapeutics, & Toxicology Program
Back to the 32nd Annual Meeting and Exhibition of the AADR (March 12-15, 2003)

Top Level Search