| Seq #184 |
Friday, 27 June 2003 |
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| 1:45 PM-3:45 PM Svenska Massan G3, Symposium - Group/Division Sponsored |
| Immune Mechanisms In The Oral Cavity- Relevance To Health And Disease |
| * Poster files available online |
Sponsored by: Microbiology / Immunology and Infection Control, Oral Medicine & Pathology |
| Description: The mucosal immune system is important in resisting infection at mucosal surfaces including those of the gastrointestinal tract, the uro-genital tract, the upper respiratory tract and the oral cavity. The generation of humoral and cell mediated mucosal immune responses involves both a site of induction where the antigen enters the body, is processed and an immune response initiated and an effector site where the immune response is mounted.
Increasing evidence suggests there is regional compartmentalisation of the mucosal immune system and that a particular inductive site may be important in generating effector responses at a limited number of sites. This may have important implications in the development of efficient mucosal vaccines against oral infections and also in explaining the pattern of immunological disease affecting the oral mucosa. This symposium will bring together recent advances in the understanding of the molecular basis of regionalisation within the immune response together with modern approaches to the development of effective mucosal vaccines. Topics to be included are current concepts in the molecular basis underlying homing mechanisms of mucosal B cells, the generation of T cell reactions in the oral mucosa and the different strategies available for generating an effective immune response against oral infections including the use of exotoxins and vaccines generated in plants. This symposium is aimed at investigators in the fields of oral medicine and pathology, oral microbiology and oral immunology |
| Chairperson: P.M. FARTHING |
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1:45 PM | Chair's Opening Remarks |
| 1791 |
1:50 PM | Homing mechanisms for mucosal B cells are both generalised and regionalised.
P. BRANDTZAEG, University of Oslo, Norway |
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2:20 PM | T cell reactions in the oral mucosa
E. AHLFORS, University of Oslo, Norway |
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2:50 PM | Mucosal immunity, IgA and the control of oral infections
M.W. RUSSELL, University at Buffalo, NY, USA |
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3:15 PM | Microbial adhesion:targets for prevention of mucosal infection
C. KELLY, University of London, GKT, United Kingdom |
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