1670 Antibacterial Activity of Extracts of Several Plants against Streptococcus mutans
Y.C. PARK1, S.-I. KIM1, C.H. AN1, K.J. KYEUN1, and K.J. KIM2, 1 School of Dentistry, Iksan, South Korea, 2 Department of Oral Microbiology, Wonkwang University, Iksan, South Korea

Objectives: Dental caries is a multifactorial disease, and the factors associated with demineralization of enamel are complex. Therefore, new agents are needed to treat the dental caries. Methods: The antibacterial effect of some extracts from Panax ginseng (in Korea), Korean ginseng flower, Salivae miltiorrhizae radix, Caesalpinia sappan leaves, Curcuma longa leaves and Quercus aliena leaves against was studied in vitro. Results: The crude saponins and plant extracts from Korean ginseng flower, Salivae miltiorrhizae radix, Caesalpinia sappan leaves, Curcuma longa leaves and Quercus aliena leaves were found to inhibit the growth of S. mutans JC-2. The inhibition of salliva-coated hydroxyapatite bead adsorption depended on the concentration of the crude saponin from white ginseng roots extracts and from red ginseng roots, plant extracts from Korean ginseng flower, Salivae miltiorrhizae radix, Caesalpinia sappan leaves and Quercus aliena leaves. The plant extracts from Curcuma longa leaves did not show statistically significant change. Conclusions: These results suggest that the crude saponin extracts from Korean ginseng and plant extracts from Korean ginseng flower, Salivae miltiorrhizae radix, Caesalpinia sappan leaves and Quercus aliena leaves might have the antibacterial activity against S. mutans JC-2. Supported by a grant of No. R01-2001-00133-0 from KOREF.

Seq #174 - Oral Microbiology & Immunology I
11:00 AM-12:15 PM, Friday, 27 June 2003 Svenska Massan Exhibition Hall B

Back to the Microbiology / Immunology and Infection Control Program
Back to the 81st General Session of the International Association for Dental Research (June 25-28, 2003)

Top Level Search