2946 Enhanced Bone-to-Implant Attachment of Fluoride-modified Titanium Implants
J.E. ELLINGSEN1, H.J. RONOLD2, K.J. BOSTROM3, A. HOLMEN4, and S. HANSSON4, 1 Faculty of Dentistry, University of Oslo, Norway, 2 Oral Research Laboratory, Oslo, Norway, 3 Astra Tech AB, Mölndal, Sweden, 4 AstraTech AB, Mölndal, Sweden

The time span from implant operation to establishing of functional attachment between the implant and bone is clinically important. Modification of the titanium implant surface is one strategy for improvement of the bone response to reduce the healing time. Objective: In the present study the object was to investigate the bone attachment to titanium implants with surfaces that had been modified with respect to the surface roughness and to the surface chemistry. Methods: Four groups of coin shaped pure titanium implants were included into the study. All implants were blasted with TiO2 particles. Implants treated according to the TiOblastTM protocol served as control(group 1) whereas the other implants (groups 2,3,4)were blasted with coarser TiO2 particles; the surfaces of the implants in groups 3 and 4 were additionally treated with hydrofluoric acid. Analysis of the implant surface topography was conducted with optical profilometry. The implants (n=80) were operated into the cortical part of the tibial bone of 20 rabbits and fixated by a titanium band without any further mechanical retention. This method is only marginally influenced by shear forces. After a healing period of 8 weeks the attachment of the implants to bone was recorded by tensile testing using a Lloyds LRX Materials testing machine. Results: The Sa(µm) values of the different test groups were 0.79(Control), 1.52(Gr.2) 1.28(Gr. 3) and 1.26(Gr. 4). The pull-out values(N) were 17.11(Control), 32.20*(Gr.2), 38.23*#(Gr. 3) and 39.85*#(Gr. 4). *Significant different (p<0.05) from control (ANOVA) #Significant different (p<0.05) from group 2 (ANOVA) Conclusion: The present study demonstrated that an increase in the TiO2 blasting particle size improved the bone-to-implant attachment after a 8 week healing period. Modification of the titanium surface by hydrofluoric acid further improved this attachment demonstrating that these implants reached an improved attachment at shorter healing time.

Seq #295 - Bone Response to Surfaces/Scaffolds
1:30 PM-3:30 PM, Saturday, 28 June 2003 Svenska Massan J2

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