| 2692 Fabrication of Osteoconductive Porous Blocks Using Calcium Phosphate Glasses | ||
|
Y.-K. LEE1, Y.-S. PARK2, M.-C. KIM1, K.-M. KIM2, K.-N. KIM2, S.-H. CHOI2, and R.Z. LEGEROS3, 1 Brain Korea 21 Project for Medical Science, Yonsei University, Seoul, South Korea, 2 Yonsei University College of Dentistry, Seoul, South Korea, 3 New York University College of Dentistry, USA Objectives: Interconnective porous materials with sufficient pore size are received much attention because let the tissue penetrate into the porous block easily, thus improve the attachment between bone graft materials and tissues. In order to fabricate the osteoconductive porous blocks, polymeric sponge method was employed in this study. Methods: Calcium phosphate glass with Ca to P ratio of 0.6 was synthesized in the system CaO-CaF2-P2O5-MgO using calcium carbonate, calcium fluoride, phosphoric acid and magnesium oxide through melting and subsequent quenching, and reduced to the powders less than 40 microns. Calcium phosphate glass slurry was prepared by dissolving the prepared glass powders into the distilled water with polyvinyl alcohol, polyethylene glycol and dimethyl formamide as binder, stabilizer and drying chemical control agent, respectively. Reticulated polyurethane sponges with 50 ppi were engaged as a template in this process. They were coated with the prepared glass slurry by infiltration technique several times. The coated sponges were dried at room temperature and heated slowly up to various temperatures. Sponge as well as other organics was allowed to burn out during the heat-treatment and the residual glasses were sintered in a rigid form with maintaining the original reticulate porous structure. Results: The optimal conditions in this study were as follows; ratio between the glass powder and water was 40 to 60, amounts of addition of polyvinyl alcohol, polyethylene glycol, demethyl formamide were 8, 4, 10 wt%, respectively, and the heat-treatment temperature was 850 degrees in Celsius. The compressive strength increased about 75% after repeat heat-treatment, however, there was no significant difference. Conclusions: Porous blocks having interconnecting pores with 500-800 microns can be manufactured using a prepared calcium phosphate glasses by polymeric sponge method, which is expected osteoconductive and biodegradable bone graft materials. Supported by the Korea Ministry of Health and Welfare, Grant No. 01-PJ5-PG3-20507-0105. | ||
| Seq #272 - Properties of Implants, Tooth Structure and Other Materials 11:00 AM-12:15 PM, Saturday, 28 June 2003 Svenska Massan Exhibition Hall B | ||
|
Back to the Dental Materials: VIII - Others-Non-metallic Program
| ||