| 0896 Clinical Evaluation of Two Teeth-whitening Products | ||
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M.S. GINIGER1, O. STRINGER2, and S.A. NATHOO2, 1 University of Medicine and Dentistry of New Jersey, Newark, USA, 2 Oral Health Clinical Services LLC, Piscataway, NJ, USA Objective: The purpose of this parallel, randomized, blind clinical trial was to examine the clinical safety and the tooth whitening efficacy of a peroxide containing brush-on tooth gel (LCH - Liquid Crystal HydrogelTM) versus a popular whitening toothpaste (CEW - CrestTM Extra Whitening). Methods: Twenty healthy subjects with tooth shade darker than A3 on the VitaTM shade guide were selected to participate in this clinical trial. The subjects were divided into two equal groups based on the baseline tooth color and assigned one of two products (LCH or CEW). All subjects were instructed to brush twice daily for two minutes each for a period of three weeks using a regular toothbrush (ColgateTM Diamond Head). Product safety was determined by clinical examinations of the oral cavity. Teeth whitening efficacy was determined using subjective shade guide methods and objective (Minolta CR221 colorimeter) methods. Colorimeter measurements were obtained in the L*, a*, b* color space for maxillary anterior teeth using the method of Tavares et al. (J. Dent Res, 2002, 81:2440). The change in tooth color was calculated as a function of Delta E using the CIE L*a*b* color difference equation. Results: Clinical examinations of the oral cavity did not show adverse reactions. Shade guide evaluations showed an overall improvement of 3.95 (+/- 1.26) shades for LCH and 0.90 (+/- 1.26) shades for CEW. Colorimeter measurements confirmed the shade guide results and showed Delta E of 2.49 (+/- 0.72) for LCH and Delta E of 0.88 (+/- 2.02) for CEW. Statistical analysis by the F-test of the shade guide data and the colorimeter data showed significant post-brushing differences (p<0.05) between the two products. Conclusion: Clinical examinations, shade guide analysis and colorimeter measurements showed that Liquid Crystal HydrogelTM is safe and has a better teeth whitening effect versus the control commercially available toothpaste. | ||
| Seq #101 - Clinical Evaluations of Bleaching/Tooth Whitening 3:45 PM-5:00 PM, Thursday, 26 June 2003 Svenska Massan Exhibition Hall B | ||
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