| 2687 Chemically Modified Calcium Metaphosphate: Biocompatibility, Osteoconduction Capacity, & Biodegradability | ||
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J.H. KIM1, H.K. NA1, C.S. LEE1, T.I. KIM2, J.W. HAN2, Y. KU1, and C.P. CHUNG1, 1 Seoul National University, College of Dentistry, South Korea, 2 Seoul National University,Intellectual Biointerface Engineering Center, South Korea Objectives: The purpose of this study was to investigate biocompatibility, osteo-conduction capacity and biodegradability of Na2O, K2O added calcium metaphosphate(CMP). Methods:Beta CMP was obtained by thermal treatment of anhydrous Ca2(H2PO4)2. Na2O and K2O were added to CMP. Biodegradability of CMP,Na2O-CMP and K2O-CMP in Tris-buffer solution and simulated body fluid for 30 days was measured. 24 Newzealand white rabbits were used. Groups were negative control, Bio-Oss, CMP , 5% Na2O-CMP and 5% K2O-CMP. Graft materials were placed in rabbit parietal bone defects and sacrificed at 3 and 6 months.The amount of new bone formation was mesured under LM. All data was analysed by ANOVA. Results:Biodegradability of Na2O-CMP and K2O-CMP was greater than that of CMP. All CMP grafts were biocompatible and osteoconductive. Histomorphometric data showed that there was no significant difference in new bone formation between all CMP group and Bio-Oss group. Conclusions:5% Na2O-CMP and 5% K2O-CMP would be a good condidate for bone substitution materials. | ||
| Seq #272 - Properties of Implants, Tooth Structure and Other Materials 11:00 AM-12:15 PM, Saturday, 28 June 2003 Svenska Massan Exhibition Hall B | ||
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Back to the Dental Materials: VIII - Others-Non-metallic Program
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