| 2941 Determinant Surface Properties of Oxidized Implants for Reinforced Osseointegration | ||
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Y.-T. SUL, Göteborg University, Sweden, and C. JOHANSSON, University of G?eborg, Sweden The surface oxide properties of titanium implants have been known to play an important role in rapid and strong osseointegration via mechanical interlocking and biochemical bonding mechanism (Sul Thesis, Göteborg Uni., 2002). The objective: to determine the significances of the oxide properties of titanium implants in the bone response. Methods: The surface characteristics of oxidized and turned implants (controls) (C.p grade 1) were measured with Auger Electron Spectroscopy, Scanning Electron Microscopy, TopScan 3D®, thin-film X-ray diffractometry, Raman spectroscopy and X-ray Photoelectron Spectroscopy respectively. A total of 176 screw implants were inserted in tibia and femur of twenty-two rabbits for 6 weeks. The bone response was evaluated with biomechanical tests and histomorphometry. Results: Porous oxide structured implants with an oxide thickness of more than 600 nm showed stronger bone responses than non-porous oxide structured implants with 17 –200 nm thickness: Removal torque (8±2Ncm (n=18) vs. 12±3Ncm (n=26). Mann-Whitney test, p=0.0001) and BMC (bone to metal contact) in all threads (24±12% (n=16) vs. 20±9% (n=44). p=0.033). Of the chemically modified implants with a porous oxide thickness of about 1µm, the Ca incorporated implants characterizing as anatase structure showed highly significant differences in removal torque (19±3Ncm, n=17) compared to controls (13±2Ncm, n=15. Tukey test, p=0.0001) and P implants (15±4Ncm, n=16. p=0.005). The BMC of Ca implants in all implant threads also demonstrated significant differences in comparison with controls (Tukey test, p=0.0001): 19.8±8 in controls, 39±12 in S incorporated implants, 44±10 in P incorporated implants and 49±12% in Ca incorporated implants. Conclusion: The present results indicated that chemical and morphological properties of oxidized implants may were of great importance in determination of osseointegration. | ||
| Seq #295 - Bone Response to Surfaces/Scaffolds 1:30 PM-3:30 PM, Saturday, 28 June 2003 Svenska Massan J2 | ||
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