| 1358 Efficacy of Implant-supported Maxillofacial Prostheses: Study Design and Sample Characteristics | ||
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K. KAPUR1, N. GARRETT2, E.D. ROUMANAS1, E. FREYMILLER2, J. BEUMER1, and R.C.. MCFARLAND1, 1 UCLA School of Dentistry, Weintraub Center, Los Angeles, CA, USA, 2 UCLA School of Dentistry, Weintraub Center & VA Greater Los Angeles Healthcare System, CA, USA Objectives: Although implant-supported prostheses have been recommended for dental rehabilitation following partial mandibulectomy or maxillectomy, there is limited evidence to indicate superiority over conventional prostheses. A within-subject longitudinal clinical trial was undertaken to determine if these two treatment modalities restore oral functions and quality of life to the level that existed just prior to ablative cancer surgery. Methods: A total of 46 participants needing a partial mandibulectomy with free-flap reconstruction and 20 a partial maxillectomy were recruited from the UCLA Maxillofacial Clinic. Participants submitted to the same series of orofacial and dental examinations and subjective and objective measurements of oral functions, food preferences, patient satisfaction and chewing preferences at four intervals: (a) before ablative surgery; (b) with interim prostheses prior to the insertion of conventional prostheses; (c) 4 months after the insertion of conventional prostheses; and, (d) 4 months after the insertion of implant-supported prostheses. Results: Of the 66 participants, 51 presented with primary and 15 with recurrent disease. They ranged in age from 19 to 89 years of age (mean = 63 years), 34 were women and 32 were men, and 42 had a positive history for smoking. In the mandibulectomy group prior to surgery, 39 were dentate (mean of 24 teeth) and 7 were completely edentulous. After surgery, the mean number of teeth declined by 4.6 teeth in the dentates. Only participants with an edentulous maxilla were enrolled in the maxillectomy group. Prior to placement of the conventional prostheses, 13 participants were lost to follow-up due to recurrent disease, 2 died and 2 dropped out. Conclusions: The significant loss of participants due to recurrent disease and death before completion of conventional prostheses indicates the need for guidelines to scrutinize patients prior to initiating any extensive dental treatment. Supported by NIDCR Grant R01DE11255 and VA Medical Research Service. | ||
| Seq #148 - Maxillofacial Treatment, Masticatory Performance and Forces, Speech 9:00 AM-11:00 AM, Friday, 27 June 2003 Svenska Massan F1 | ||
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