Objectives: The purpose of this in vitro study was to evaluate fluoride release and uptake of three glass ionomer cementes (Ketac Molar – ESPE; Fuji IX – G.C. Corp.; and ChemFlex – Dentsply) developed for the A.R.T. (Atraumatic Restaurative Treatment) and compare to one conventional glass ionomer cement (Vidrion R – S.S. White) and one silver-reinforced glass ionomer cement (Vidrion N – S.S.White). Methods: Three specimens of each material were done in metallic molds, allowed to set for 15 minutes, protected with proper varnish and immersed in 3 ml of deionized water. The analyses was made with a fluoride ion-specific eletrode, after buffering the solution with equal amounts of TISAB, at 1, 2, 3, 4, 5, 6, 7, 14, 21 and 28 days. On the 29th day, the specimens were immersed in 50 mg toothpaste, dissolved in 3 ml of deionized water, for 3 minutes. They were washed for 1 minute, and then immersed again in 3 ml of deionized water. This procedure was done for 3 days, to evaluate fluoride uptake of each material. Results: The data showed that there was significant difference in fluoride release of Vidrion R when compared to all materials. There was no significant difference between Fuji IX, Ketac Molar and Chem Flex. Vidrion N was the only one that didn't show fluoride uptake from the toothpaste. Conclusions: The glass ionomer cements developed for A.R.T. release smaller amounts of fluoride than the conventional and silver-modified cements. All materials uptake fluoride from the dentifrice, except the silver modified cement.

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